20 May 2026
A multimodal analysis reveals a ‘U-shaped’ association between sleep duration and biological ageing across various organ systems, with too much or not enough sleep being linked with accelerated organ ageing. The study also shows that biological ageing differentially mediates the relationship between extremes in sleep duration and late-life depression.
This is a summary of: The MULTI Consortium et al. Sleep chart of biological ageing clocks in middle and late life. Nature https://doi.org/10.1038/s41586-026-10524-5 (2026).
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