Scientists have identified genetic variants that may make some people less responsive to GLP-1 drugs used to treat Type 2 diabetes. Roughly 10% of the population carries these variants, which appear to cause a mysterious form of "GLP-1 resistance." In several clinical trials, carriers were significantly less likely to reach healthy blood sugar targets while taking GLP-1 medications.

A recent trial is the latest to suggest that GLP-1s aren't just for treating diabetes and obesity.

GLP-1 drugs may curb addiction and craving, making some patients less likely to drink alcohol. It could ease anxiety, compulsive thinking and emotional distress | World News

Scientists have identified genetic variants that may make some people less responsive to GLP-1 drugs used to treat Type 2 diabetes. Roughly 10% of the population carries these…