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Some of Earth’s microbes likely to hitch a ride to space with human explorers could survive in the shaded nooks and crannies of the Moon’s South Pole region, NASA scientists say.
Published on Aug. 19, 2026, in Science Advances, these findings highlight a need to better understand microbial persistence in extreme lunar environments. As humans build a permanent presence on the Moon, it may become difficult to distinguish ancient lunar chemistry from contamination delivered by visiting astronauts. The concern extends beyond the Moon and on to Mars, scientists say.
“Humans are natural explorers, and with them come their voices, their memories … and their microbes,” said Prabal Saxena, a planetary scientist who led the study from NASA’s Goddard Space Flight Center in Greenbelt, Maryland. “For some scientists, myself included, that reality can be unsettling. But it also creates an opportunity to turn an imperfect situation into a useful experiment.”
Bringing microbes along is unavoidable: Humans have, on average, 1 million bacteria living on each patch of skin the size of a pencil eraser, for example. These bacteria vent from spacesuits and habitats. Though the paper’s authors worry about contamination interfering with the search for chemical clues to ancient geology or biology, they also argue that the Moon should be used as a natural lab. In shaded areas around the South Pole, scientists could carefully test the real-life limits of microbial survival in an environment that can’t easily be reproduced on Earth.
