Does stopping a GLP-1 really doom you to regain all the weight?A trio of recent studies suggest that some people can keep the weight off. In the original clinical trials looking at GLP-1s for weight loss, patients gained back most of the weight after stopping treatment. Allie Sullberg for NBC NewsJuly 17, 2026, 5:00 AM EDTBy Simar BajajBrandon Chargoy, 31, has struggled with his weight most of his life, cycling through crash diets and fitness fads without much success. But after he was diagnosed with Type 2 diabetes, his doctor put him on semaglutide.Just a moment.We are getting your experience ready.