The Buffalo Bills take on the Houston Texans in Week 1 of the 2026 season and the NFL experts aren’t sold on them as they hit the road for the opener.

Here are four bold predictions for the Buffalo Bills as they face the Houston Texans in Week 1 of thre 2026 season.

The former Bills' first-round pick has had a rough stretch of play down in Houston, Texas, since 2018.