Google Deepmind has used the AlphaGenome Atlas to predict what each of the roughly nine billion possible single-letter changes in the human genome could do. The dataset spans one petabyte, more than 30 times the size of the AlphaFold database. In one epilepsy case, the atlas helped pinpoint a previously overlooked variant as the likely cause.

AI model AlphaGenome forecasts the consequences of altering every single DNA letter in the human genome.

We’re introducing AlphaGenome Atlas, a database predicting the effects of every possible single nucleotide variant in the human genome.

AlphaGenome Atlas predicts the effect of any single change in the fundamental structure of DNA