US drugmakers Merck and Moderna on Wednesday said a personalized cancer treatment had shown success in reducing the recurrence of melanoma tumors in a late-stage trial hailed by experts as a “breakthrough.”The drug, called “intismeran autogene,” is based on the same messenger RNA (mRNA) technology b

News of first positive large late-stage trial result for drug could signal new era for treating solid-tumor cancers, with tests underway for lung, breast and pancreatic cancers

A phase 3 trial found that a combination of intismeran autogene plus pembrolizumab improved recurrence-free and distant metastasis-free survival in patients with high-risk…