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Aneuploidy selects for the acquisition of driver genes in breast cancer - Nature
Screening of chromosome arm-level aneuploidies uncovers that these alterations select for specific basal-like breast cancer driver genes, including PLGRKT, an oncogene whose tumour-promoting activity is associated with highly stress-resistant mitochondria and enhanced detoxification of reactive oxygen species.
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Aneuploidy selects for the acquisition of driver genes in breast cancer - Nature
Screening of chromosome arm-level aneuploidies uncovers that these alterations select for specific basal-like breast cancer driver genes, including PLGRKT, an oncogene whose…
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Breast cancer driver genes found by screening chromosome aberrations in vivo
Altered expression of many drivers identified in the in vivo CRISPR screen did not alter cell behaviour in vitro.