Senate Republicans say there are many unanswered questions about the deal and question inclusion of funds for Iran

Vance on CNBC's "Squawk Box" expressed confidence that America has "all the cards" in subsequent talks with Iran.

When discussing Israel's involvement in the agreement, Vance noted, “I believe there are elements in Israel who like the agreement.”

Vice President JD Vance is expected to head to Europe later this week to sign a memorandum of understanding with Iran.