Ardie Savea will miss the fourth and final Test of Rugby's Greatest Rivalry in Baltimore against the Springboks after picking up a shoulder injury in the third match in Soweto on Saturday.

The All Blacks were left to rue missed opportunities and the loss of inspirational captain Ardie Savea as they went down 29-24 to the Springboks at FNB Stadium in Soweto on Saturday evening.

Savea was forced from the field with a serious shoulder injury after a ruck and is set to miss the fourth Test in Baltimore this coming Saturday. Head coach Dave Rennie confirmed his captain will be sidelined as New Zealand look to salvage a result from the series.

The Springboks took an unassailable 2-1 lead in Johannesburg and will be the happier side on the plane heading to the United States for the fourth and final Test of Rugby’s Greatest Rivalry.

For Rennie, the defeat was particularly frustrating given the momentum the All Blacks had built early in the contest. New Zealand played with pace and stretched the Springboks, but a series of errors allowed the hosts to slow the game down and wrestle back control.