Small trial targeted liver proteins that play a part in the regulation of lipid levels.
01 September 2026
Small trial targeted liver proteins that play a part in the regulation of lipid levels.
Deposits of cholesterol (yellow; artist’s illustration) and other substances can clog up arteries. Credit: Springer Medizin/Science Photo Library
A single dose of a CRISPR gene-editing therapy reduces levels of harmful lipids — namely cholesterol and triglycerides — in the blood for at least one year1.
Access options
A One-Time Treatment for High Cholesterol Shows Promising Results
Snipping a gene to reduce bad cholesterol for life looks possible | CNN
CRISPR Therapeutics to pursue highest dose of its lipid lowering gene editing therapy
DNA treatment cuts bad cholesterol by nearly 50% without statins
Científicos logran bajar el colesterol y los triglicéridos en un 50 % durante todo un año mediante una modificación genética: no hubo efectos adversos
Una edición genética mostró resultados prometedores contra el colesterol alto
Experimental One-Dose Treatment Cuts 'Bad' Cholesterol by 52% in First Human Trial
Free cholesterol test available at pharmacies in weeks
Gentherapie gegen hohe Cholesterinwerte – eine Spritze mit lebenslanger Wirkung
Plozasiran Notches Big Wins in Severe Hypertriglyceridemia
A CRISPR-based gene-editing therapy could be a one-and-done treatment for high cholesterol and high triglycerides, a study…
Gene editing reduced cholesterol by about 50% in an extremely small sample of patients over a year of follow-up, according to a…
Separate trials using CRISPR and base editing to silence lipid genes show drastic drops in LDL-C without daily medication.
MUNICH — CRISPR Therapeutics’ gene editing candidate showed mixed durability results a year after patients were dosed, according…
Patients show 52 per cent drop in bad cholesterol levels within six months
A recent trial of an experimental gene therapy significantly lowered participants’ ‘bad’ cholesterol after just one injection.
