22 June 2026
The finding that spermine molecules in cells bind to iron to prevent it unleashing ferroptosis, a type of cell death, opens up strategies for treating tissue damage and cancer.
By
Amaia Zabala-Letona0 &
Arkaitz Carracedo1
The finding that spermine molecules in cells bind to iron to prevent it unleashing ferroptosis, a type of cell death, opens up strategies for treating tissue damage and cancer.
22 June 2026
The finding that spermine molecules in cells bind to iron to prevent it unleashing ferroptosis, a type of cell death, opens up strategies for treating tissue damage and cancer.
By
Amaia Zabala-Letona0 &
Arkaitz Carracedo1

A non-canonical metabolic route for spermine synthesis mediated by ALDH18A1 limits iron availability and lipid peroxidation in…

Cells use a little-known molecule to protect themselves from iron overload

Switching off an enzyme that plays an important role in sugar metabolism, glycolysis, would normally be expected to cause serious…

Researchers found a new way to kill harmful “zombie” cells that linger after chemotherapy and help cancers become more…

Iron metabolism is strongly connected to oxidative stress, the excessive production of reactive oxygen species and other…

Une équipe de l’Institut Curie, à Paris, a fabriqué un composé qui cible le fer accumulé dans les cellules tumorales résistantes…