June 05, 2026
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Individuals in middle age with higher levels of plasma amyloid-beta 42, amyloid-beta 40 and phosphorylated-tau 217 demonstrated worse cognitive performance and accelerated cognitive decline, according to data published in The Lancet.“We already know that Alzheimer’s disease pathophysiology can begin decades before symptoms arise,” Xiaqing Jiang, PhD, a postdoctoral scholar in
June 05, 2026
5 min read
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Slower processing speed, executive function may be earliest signals of waning cognition

Alzheimer's disease, a progressive neurodegenerative disorder that affects millions worldwide, has a long preclinical stage.

A study in the Lancet looked at whether a blood test could indicate the most common form of dementia and diagnose people decades…

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The findings show that Alzheimer’s may be present in midlife and already linked to cognitive differences, researchers said.

A blood test may detect Alzheimer's signs decades early, revealing potential for early intervention and risk factor management.