A mother has described her harrowing fight to save her 22-year-old daughter from a fatal ketamine addiction.Isabelle Sapherson-Moralee, known as Izzy, died in agony after her body succumbed to the effects of five years of Class B drug abuse, an inquest has heard. Her mother, Ann Moralee, spent 18 months desperately seeking help for Ms Sapherson-Moralee, even warning health officials that her daughter’s life was in peril. Ms Sapherson-Moralee, who endured chronic pain and a damaged bladder from her addiction, discharged herself from hospital two days before her death. In her final moments, as Ms Moralee cared for her, she pleaded with her daughter to allow her to call an ambulance.She told her daughter's inquest: “I kept asking her, ‘please let me phone an ambulance’ but she said 'no more hospitals mum, I can't do it anymore'.“She knew she was dying that last 48 hours.“She died 36 hours after she got home. She was freezing cold, shallow breathing. I checked on her and she was cold.”Isabelle Sapherson-Moralee died after a battle with ketamine addiction (BNPS)The mother said when she doing CPR and on the phone to 999 she told the call handler: “I said she's going to die, I told everybody she was going to die and now here we are and she's dead.”Ms Moralee, a flight attendant and former nurse, added: “I have saved a lot of lives in my career, both as a nurse and flight attendant, but ultimately I couldn't save my daughter.”There has been an alarming rise in ketamine abuse by young people in the UK over the last few years.Figures show that since 2015 ketamine usage has increased by 251.85 per cent, the greatest increase in the use of a single drug in that period.Ketamine, also known as 'K' and 'Special K', has been linked to dozens of student deaths over the past few years.Ms Sapherson-Moralee, who worked as an estate agent, started taking the drug regularly during the Covid lockdowns in 2020 when she moved in with her boyfriend, the inquest heard.Ms Moralee, from Wimborne, Dorset, said she did not discover her daughter had been taking it until the end of 2023 when it had gotten “out of control and she couldn't hide it anymore”.The drug use had damaged Ms Sapherson-Moralee's bladder and caused her to become incontinent about a year before she died.Her mother said it was so bad she spent £500 a month on incontinence pads and Ms Sapherson-Moralee had to stop working about six months before her death.Ms Moralee told the inquest she felt health officials could have done more to help her daughter and had “missed opportunities”.Ann Moralee leaving the inquest (BNPS)After a bad experience with a urologist at Salisbury District Hospital who Ms Moralee said was “vile” to Ms Sapherson-Moralee, she said her daughter no longer trusted doctors.She said: “From then on she had no trust in hospitals or doctors. She was just seen as a ketamine addict and everything else was ignored, especially her back pain.“I spent up to £500 a month on incontinence pads, we asked for help from the bladder and bowel people but they discharged her, as did the weight-loss team who said she didn't have an eating disorder. Then she really just gave up.”Ms Moralee said she tried to get her daughter into rehab using her private medical insurance and looked at going to America for treatment.She said there was a 'last chance' to save her daughter when she was arrested for suspected ketamine possession.She felt then Ms Sapherson-Moralee should have been sectioned under the Mental Health Act for her own protection.She said: “She couldn't walk, she was disorientated - that was the last opportunity to save her. They had a duty of care, they should have applied the Mental Health Act.“She was deemed to have capacity, my argument is how could she possibly have capacity?“I was desperately trying to help my daughter. She was so desperately ill. I think there were safeguarding concerns and missed opportunities to escalate and order an intervention.“She felt like nobody cared about her anymore, they just saw an addict.”Ms Sapherson-Moralee was admitted to hospital in March but even then and despite her poor health she was still able to get hold of and take ketamine.Ms Moralee said: “In her last hospital stay she was caught on the ward twice with ketamine, I followed her out of the building and tried to get the number plate of whoever was supplying my sick child with ketamine.”Ms Sapherson-Moralee was then admitted to A&E on 24 April 2025 before discharging herself. Ms Moralee said: “I kept asking Ms Sapherson-Moralee 'please let me phone the ambulance'. She said 'no more hospitals mum, I just want to be at home with you, I can't do it anymore'. Because of all the capacity stuff, she would have refused to go.“So I made her hot water bottles, made her some French toast, she didn't eat much.”When the family's lawyer asked her 'did she want to get better?' Ms Moralee said: “Yes, she said I'm going to get better, I'm going to do a psychology course then I want to help other children like me.“Nobody should have to go through what I have been through. Her goal was to get better.”Ms Sapherson-Moralee's cause of death was given as respiratory depression due to combined severe morphine and gabapentin toxicity.Both pain drugs showed higher than normal therapeutic levels in her blood and the gabapentin would have exacerbated the toxic effects of the morphine.The post mortem examination also found she had biliary sepsis, localised sepsis in the liver, which may have been a contributing factor but did not cause her death.The inquest also heard from Scott Davey from Reach, a drug and alcohol support charity that was working with Ms Sapherson-Moralee before her death.Coroner Brendan Allen asked if in his experience users got 'trapped in a vicious cycle' where the ketamine causes damage but users then increase the usage to relieve the pain caused by the damage.Mr Davey said: “Yes, ketamine normally starts as recreational. The dissociative factors of it mean it can be used to mask mental health, external factors going on stresses with family, work. It becomes habitual.“It is very cheap, accessible, that plays into it massively. It's not the acute effect, it's the long-term effect where it's done physical damage and then being used to manage the pain, it's a catch 22.”Mr Davey said there had been an increase in ketamine users in the two years he had been with the charity.Ms Moralee added: “Ms Sapherson-Moralee was a beautiful, funny girl, highly intelligent, a talented photographer and dancer.“But as beautiful and smart as she was, she was also a master manipulator. The guys (at her GP practice and Reach) did everything they possibly could.”The inquest in Bournemouth continues.