Shimon Sakaguchi won the 2025 Nobel Prize in Medicine for research on the immune system and the prevention of serious autoimmune diseases
Shimon Sakaguchi, the Japanese immunologist who won this year’s Nobel Prize in medicine, said on Monday he hoped the award would help further advance research and patient care.
“I sincerely hope that this award will serve as an opportunity for this field to develop further … in a direction where it can be applied in actual bedside and clinical settings,” Sakaguchi, a 74-year-old distinguished professor at Osaka University, told a news conference.
Sakaguchi was jointly awarded the 2025 Nobel Prize in Medicine alongside American scientists Mary Brunkow and Fred Ramsdell for their research into how the immune system is kept in check by identifying its “security guards”, the Nobel jury said.
Their discoveries have been decisive for understanding how the immune system functions and why we do not all develop serious autoimmune diseases.











