MIAMI, Sept. 11 (UPI) -- Saquon Barkley is among my five fantasy football running backs to avoid in lineups in Week 2 of the 2025 NFL season.

I know, I know. This headline might make some spit coffee on computer screens, but hear me out. Barkley likely isn't leaving your starting lineup in most cases, but if you play daily fantasy football, or happen to have a loaded roster and are in a smaller league with several solid running back options, you should consider alternatives.

Read below for my reasoning on -- potentially -- benching the Philadelphia Eagles' star running back. Aaron Jones, Alvin Kamara, Jerome Ford and Austin Ekeler are among my other running backs to avoid for Week 2.

My full Top 50 running back rankings for Week 2 are listed below. Jahmyr Gibbs tops this week's list. Christian McCaffrey, Derrick Henry, James Conner and Kyren Williams join Gibbs in my Top 5. Bijan Robinson, De'Von Achane, Jonathan Taylor, Chase Brown and Bucky Irving are my other Top 10 options.

Read about my four must-start wide receivers and find those Top-50 rankings here. My favorite adds and drops from this week's waiver wire/free agency pool can be found here.