1 of 6 | Philadelphia Eagles running back Saquon Barkley (26) slips past Los Angeles Rams defenders in the third quarter of NFL action Sunday at Lincoln Financial Field in Philadelphia. Photo by Laurence Kesterson/UPI | License Photo
MIAMI, Sept. 24 (UPI) -- Jonathan Taylor and Saquon Barkley lead my Top-50 fantasy football running back rankings for Week 4 of the 2025 season.
Christian McCaffrey, Derrick Henry and Bijan Robinson join Taylor and Barkley inside my Top 5. De'Von Achane, James Cook, Jordan Mason, Kyren Williams and Jahmyr Gibbs are my other Top-10 options.
My Top 20 quarterback rankings and Top-50 wide receiver rankings for Week 4 can be found here. My waiver-wire and free agent targets for Week 4 are available here.
All of my positional rankings will be updated until Week 4 kickoffs. Players also will be moved out of or adjusted within the rankings based on injuries.
