A Philadelphia medical museum accidentally dug up a decades-old mystery after discovering two unidentified infant skulls in its collection of human remains.

Staff at the Mütter Museum said they were stunned to make the find during an audit of its 6,600 human remains in November, buried deep in a box in its library.

In notes accompanying the bodies, a pathologist had written that they were from a harrowing case in the 1980s that captured international headlines - an elderly woman who admitted to having five dead babies in her attic.

According to the Philadelphia Inquirer, staff at the museum searched newspaper archives to discover that the skulls were linked to the notorious case of an elderly spinster named Stella Williamson, who died in 1980.

It appeared that the two skulls had been among five found in Williamson's attic, but were somehow lost in transit and donated to the museum.