With tears filling his eyes and his body failing beneath him, you couldn’t help but feel Sunday’s US Open defeat marked a pivotal moment in Novak Djokovic’s career.

TAMARA PRENN IN NEW YORK: Not since the 2006 Australian Open has the Serbian serial champion fallen at the first time of asking at a major

Djokovic lost having vomited and winced through a match that leaves him facing an uncertain future.