MERKT is Involved in Enabling Microglia to Kill Motor Neurons in ALS

Amyotrophic lateral sclerosis (ALS) is characterized by the loss of motor neurons. Aggregation of TDP-43 is thought to be involved in producing cell death in the brain. Here researchers present evidence in a mouse model of ALS for microglia to destroy motor neurons, and identify key cell surface features that enable this activity. Whether the...

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