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From growth to function: Gene helps human heart cells decide when to mature
Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains one of the greatest challenges in cardiovascular biology. Leveraging human induced pluripotent stem (iPS) cell technology, a team led by Associate Professor Yoshinori Yoshida (Department of Clinical Application, CiRA, Kyoto University) and Associate Professor Antonio Lucena-Cacace (WPI-PRIMe, The University of Osaka) has identified PRDM16 as an important regulator governing the balance between proliferation and maturation in human iPSC-derived cardiomyocytes.
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medicalxpress.com
From growth to function: Gene helps human heart cells decide when to mature
Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains one of the greatest challenges in…
- ·
eurekalert.org
From growth to function: PRDM16 helps human heart cells decide when to mature
Understanding how heart muscle cells stop dividing and acquire the characteristics needed to sustain lifelong cardiac function remains one of the greatest challenges in…