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Intestinal stem cells count self-renewal divisions to switch multipotency - Nature
In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing an enteroendocrine mother cell every ninth division.
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Intestinal stem cells count self-renewal divisions to switch multipotency - Nature
In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing…
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Intestinal stem cells count to eight divisions to maintain cell ratios
In the fly gut, stem cells keep the balance of cell types by undergoing eight rounds of cell division to form absorptive cells, then one round to form secretory cells.