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Background genetics and new mutations interact to direct cancer evolution
Studies of mice show that cancer dynamics depend on an interplay between the inherited genome and acquired mutations.
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Background genetics and new mutations interact to direct cancer evolution
Studies of mice show that cancer dynamics depend on an interplay between the inherited genome and acquired mutations.
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Genetic background sets the trajectory of experimental cancer evolution - Nature
Experimentally replaying tumour evolution in divergent mouse strains reveals the importance of interactions between genetic ancestry and acquired cancer-driving mutations in…