Currently, the treatment for moyamoya disease (MMD), a condition characterized by the blockade of the internal carotid artery, is revascularization surgery. However, this surgery can lead to cerebral ischemia for which limited predictive tools are available. Now, a group of Chinese researchers identified preoperative blockage of the major intracranial arteries as a risk factor for cerebral infarction after combined revascularization surgery in MMD, paving the way for the development of novel prediction protocols.