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Navigating a crowded developing brain leaves neurons with broken DNA
As neurons migrate to their final destinations in the forming brain, their DNA gets damaged. The brain has evolved a fix, but there can be lasting consequences if repair fails.
Raccontata da
nature.com
Timeline cronologica
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Navigating a crowded developing brain leaves neurons with broken DNA
As neurons migrate to their final destinations in the forming brain, their DNA gets damaged. The brain has evolved a fix, but there can be lasting consequences if repair fails.
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Confined migration induces non-lethal DNA damage in developing neurons - Nature
The migration of neurons in developing cerebral and cerebellar cortices is accompanied by massive DNA double-strand breaks due to mechanostress during passage through narrow…