Using patient-derived cardiac tissue and stem cell-based models, the team of translational researchers demonstrated that targeting the genetic cause of disease improved cellular abnormalities and identified the biological pathways involved. The results of this study were published in Signal Transduction and Targeted Therapy.

Treatments aim to bulk up failing hearts to restore their vigour – but can the field move on from past controversy?

Using patient-derived cardiac tissue and stem cell-based models, the team of translational researchers demonstrated that targeting the genetic cause of disease improved cellular…