The immune system declines with age, and this causes more than just a progressive failure to adequately defend against infectious pathogens. The immune system is deeply involved in normal tissue function, maintenance, and regeneration. It is also responsible for destroying senescent and potentially cancerous cells throughout the body. Thus immune decline both degrades tissue function...

With advancing age the composition of the gut microbiome changes in detrimental ways and the immune system becomes progressively incapable. These two aspects of aging do not…

Far too little research into infectious disease and the development of vaccines and other approaches to therapy employs old animals. It is accepted that infectious disease becomes…

The immune system declines with age, and this causes more than just a progressive failure to adequately defend against infectious pathogens. The immune system is deeply involved…