Senator Bill Cassidy (R-LA) came in third in Louisiana's Republican Senate primary on Saturday - marking the first time in nearly 15 years that a sitting US Senator has lost a primary in a regularly scheduled election. Instead, Trump-endorsed Rep. Julia Letlow led with ~45% of the vote, while state Treasurer John Fleming came in second at 28%.Letlow and Fleming will now face off in a June 27 runoff. Cassidy was a notable fan of Obamacare, and voted to convict Trump during impeachment over the Jan. 6, 2021 Capitol riot. He also helped sink Casey Means' nomination for surgeon general, which drew sharp criticism from Health Secretary Robert F. Kennedy Jr, and his MAHA movement. He's been labeled a big pharma shill by opponents. With Bill Cassidy's primary defeat last night, @PeterKolchinsky has one less Big Pharma puppet to play with in Congress. https://t.co/NLmnYVaIXQ

Sen. Bill Cassidy of Louisiana faces two challengers — one endorsed by the president — in Saturday’s primary, five years after voting to convict Trump.

Louisiana voters will participate in a revamped and stripped-down state primary Saturday and decide the political fate of an embattled Republican U.S. senator targeted for defeat…

If GOP voters are looking for guidance from party leaders on who to side with in the crowded Louisiana primary, they’re in for mixed messages.