The first week of the 2026 NFL season is a weird one, so we’re focusing on injuries impacting the Wednesday and Thursday games first, as practice reports will provide more clarity as the week progresses. As those reports surface, we’ll update this file with the most fantasy-relevant NFL injuries ahead of Week 1. Refer to the table below the analysis for a player’s latest status.Below you can also find weather forecasts for every game and our customizable start/sit tool. Check back for the latest updates, and catch up with our experts and other fantasy footballers in our Discord server.This story was last updated at 9:25 a.m. ET, Sept. 9.Injury/Inactive report and analysisWednesday nightTreVeyon Henderson, RB, NE: Henderson didn’t practice early in the week and has been officially ruled out. Rhamondre Stevenson will see more volume, but remains an RB2, given Seattle’s rush defense.Zach Charbonnet, RB, SEA: With Charbonnet on the PUP list, Jadarian Price will get a chance to lead the backfield; however George Holani could factor in, and the Seahawks have, according to Jake Ciely, “alluded to using more two-tight end sets.” Price is more Flex than RB2 in Week 1.Thursday nightGeorge Kittle, TE, SF: Kittle is tracking toward playing, according to The Athletic’s Matt Barrows and Vic Tafur. If he takes the field, Kittle could have his workload monitored, but he’s currently Ciely’s TE7.Sunday 1 p.m. Tank Dell, WR, HOU: With Dell on IR, new addition Kayshon Boutte could see more work. One thing’s for sure, Nico Collins should get all the looks he can handle and has top-five potential this week.Jonathon Brooks, Chuba Hubbard, RBs, CAR: Brooks’ and Hubbard’s values this week are dependent on the health of each. If both are healthy, Brooks gets the nod as a possible Flex. If Brooks sits, Hubbard moves into Flex territory.Rome Odunze, Luther Burden, WRs, CHI: Odunze has been described as “day-to-day,” which isn’t the best news. If he sits, Burden is squarely in WR2 territory and TE Colston Loveland, who could finish as a top-three TE in Week 1, gets a boost too.