The best medicines go exactly where they’re needed in the body— and nowhere else.
For a drug to have a positive effect, it must reach its target in the body. Even the most potent agent will be rendered useless if the biochemical headwinds prove too great — or if a person simply chooses not to take their medicine.
Nature 657, S1 (2026)
doi: https://doi.org/10.1038/d41586-026-02653-8
These six advances could change how drugs are delivered
Drug-delivering particles aim to breach the blood–brain barrier
The inability to get drugs into the brain has impeded the treatment of cancer and neurodegenerative diseases for decades.…
As generative AI captures public attention, a different kind of AI is reshaping drug discovery. Machine learning models are…
AI is identifying new therapeutics targets faster than ever. But this speed is exposing physical bottlenecks in the lab, and a…
There is a version of this story that ends well.A class of molecules with genuine biological potential, freed from bureaucratic…
Anticancer drugs could be manufactured and delivered by modified microorganisms.
Therapies that target mitochondria and other organelles are being put to test in the clinic.
