Week 1 of the NFL and fantasy football kicks off tomorrow, and your rosters are pretty much set. However, there could still be some valuable assets sitting on the waiver wire. We are going to take a look at the running backs you should consider picking up off the waiver wire prior to the start of Week 1.

Week 1 Waiver Wire Running BacksKaelon Black, San Francisco 49ers

With Christian McCaffrey failing to practice on Monday due to "tightness", and the 49ers playing on Thursday Night Football in Melbourne, Australia, we'd strongly advise you to play it safe and scoop up his handcuff.

We view black as the direct handcuff to CMC, although some would argue it could be Jordan James. Nevertheless, Black is the guy that we would be targeting in this situation.

Even if McCaffrey is listed as a full participant in practice today and is a full-go for Thursday, McCaffrey might be the most important running back in the league to handcuff. He's a 30-year-old running back with an extensive injury history, coming off the largest workload of his life and currently on the injury report. Make sure you go get Black.