U.S. stocks were lower, with the Dow Jones index falling around 400 points on Monday.

Shares of Ascendis Pharma A/S (NASDAQ:ASND) rose sharply on Monday.

On Sunday, BioMarin Pharmaceutical Inc. (NASDAQ:BMRN) reached a binding settlement with Ascendis Pharma to resolve all global patent disputes regarding the medication Yuviwel.

Ascendis Pharma shares jumped 5.7% to $262.12 on Monday.

Here are some other big stocks recording gains in today’s session.