Denosumab may confer lower osteoarthritis risk than oral bisphosphonates

Older adults with osteoporosis may have decreased risk for osteoarthritis if they initiate therapy with denosumab compared with an oral bisphosphonate, according to study data published in the Journal of Bone and Mineral Research. In a target trial emulation study, researchers compared incident osteoarthritis rates between older adults who initiated denosumab for the first time with those who