When Raghav Sehgal arrived at Yale as a graduate student several years ago, he wanted to explore the use of powerful computer science tools in cancer research. With an engineering background and a computational biology startup already under his belt, he was well prepared.But as Sehgal began his Ph.D. studies, his thesis adviser at the Yale School of Medicine posed a larger question: If you want to solve cancer or any age-related disease, such as cardiovascular disease, why not solve aging itself? “That put me on a different path,” said Sehgal, an associate research scientist in psychiatry with specialties in computational biology and bioinformatics. “As researchers, we have a long way to go in understanding the aging process and whether the steps we take to manage it really work.
Improved blood-based DNA tests indicate that these interventions seem to be the most effective at slowing the biological aging process: • Prescribed medications for metabolic control and weight management, including metformin and semaglutide. • Healthy diet and exercise combined. Researchers looked at popular diets including, the Mediterranean, low-fat, and low-carb plans.Additional research is needed to further validate the findings.
