GLP-1 drugs and surgery offer major weight-loss benefits, but behavioral programs focused on diet quality could be important for modest weight-loss goals.A Mediterranean-style diet program was no better than a control intervention for weight loss at 24 months (-3.4% vs -3.5%) in a study of primary care patients with obesity.Of note, the Alternative Healthy Eating Index-2010 score, measuring diet quality, was significantly higher in the Mediterranean-style diet group versus the control group.
A Mediterranean-style diet program did not lead to greater weight loss compared with a control intervention among primary care patients with obesity, though it did improve diet quality, the DELISH trial showed.
Missing the trial's primary endpoint, the Mediterranean-style diet group lost an average 3.4% of their body weight at 24 months compared with an average loss of 3.51% in a control group that had access to WeightWatchers (P=0.90), reported Thomas Keyserling, MD, MPH, of the UNC Center for Health Promotion and Disease Prevention in Chapel Hill, North Carolina, and colleagues.
This translated to an adjusted mean weight loss of 8.7 lbs and 8.8 lbs, respectively, though both groups fell below the 5% threshold considered clinically significant.
