PNOC008 findings support molecular profiling and personalized treatment strategies
— PNOC008 findings support molecular profiling and personalized treatment strategies
by Gregory Laub, Senior Director, Video, MedPage Today
July 29, 2026
• 3 min read
At the International Symposium on Pediatric Neuro-Oncology (ISPNO), it was reported that personalized treatment guided by deep molecular profiling produced encouraging survival outcomes in a subset of children with H3 G34-altered diffuse hemispheric glioma enrolled in the PNOC008 precision medicine trial.
What if physicians could anticipate tumor progression and base treatment decisions on that?
Experts discuss biologic targeting, dose escalation, and the promise of precision radiotherapy
A Kookmin University research team has identified previously unrecognized molecular subtypes of medulloblastoma, a rare and…
Children's Hospital of Philadelphia Researchers Develop Platform to Improve Adaptive Immune Responses in Cancer
'This was the first time we've ever shown ... retreatment is an effective strategy,' says expert
The personalized treatment encourages the immune system to attack the tumours called glioblastomas.
