Nongated chest CT scans are usually performed for reasons other than to assess cardiovascular risk.Incidental coronary artery calcium (CAC) scores extracted from nongated chest CT scans accurately predicted cardiovascular risks in a community-based cohort.Patients with moderate or severe nongated CAC had significantly higher risks of cardiovascular disease and coronary heart disease versus those with zero CAC.
Incidental coronary artery calcium (CAC) scores extracted from nongated chest CT scans accurately predicted cardiovascular risks, a cohort study showed.
Patients with moderate nongated CAC had significantly higher risks of cardiovascular disease (CVD; HR 2.31, 95% CI 1.32-4.04) and coronary heart disease (CHD; HR 2.67, 95% CI 1.14-6.27) versus those with zero CAC, and the same was true for those with severe nongated CAC (CVD: HR 2.89, 95% CI 1.68-4.96; CHD: HR 5.22, 95% CI 2.37-11.5).
Additionally, with participants having undergone gated and nongated chest CT scans on the same day, log-standardized CAC results between the two modes were highly correlated (r=0.961, P<0.001). The area under the receiver operating characteristic curves, C-statistic, and Brier scores were also statistically similar for gated and nongated CAC, reported Dhiran Verghese, MD, of Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues.
