The US Department of Commerce is searching for a new director to lead its AI governance body, the latest chapter in a revolving door of leadership that has plagued the organization since its founding. The institute, originally called the US AI Safety Institute, has now been rebranded, restructured, and left without stable leadership.

A timeline of departures and disruptions

The US AI Safety Institute launched in 2024 under the Biden administration with a clear mandate: manage the risks of advanced AI systems. Elizabeth Kelly, its first director, held the role until early February 2025, when she stepped down.

Her departure kicked off a rapid series of personnel changes. A replacement was brought in with ties to Anthropic, the AI company behind Claude. He lasted four days before being shown the door over concerns about his prior work.

The instability didn’t stop at staffing. On July 31, 2025, Commerce Secretary Howard Lutnick announced the institute would be rebranded as the Center for AI Standards and Innovation, or CAISI. The word “safety” was deliberately dropped from the name, shifting the institute’s focus from regulatory oversight toward national security and global competitiveness.