Melatonin may lower chronic pain, but it should not replace other medications

Melatonin reduced chronic musculoskeletal pain to a degree similar to pain medications like opioids, although most of the differences did not reach clinically meaningful thresholds, according to a systematic review published in PAIN.“Melatonin is already in people’s homes, it’s inexpensive, and we know it’s safe,” Kangchao Wu, a PhD student from the Charles Perkins