As summer temperatures rise and emergency department visits related to extreme heat top 100,000 Americans a year, what should people know about the dangers of heatstroke? What are the symptoms, and how can others recognize if someone needs help? What are other types of illnesses associated with extreme heat? And who is most susceptible to the ill effects of high temperatures?

To find out how to handle the heat, I spoke with CNN wellness analyst Dr. Leana Wen. Dr. Wen is an emergency physician and clinical associate professor at the George Washington University. She previously served as Baltimore’s health commissioner.

CNN: What should people know about heatstroke? What is it, and what are its symptoms?

Dr. Leana Wen: Heatstroke is a medical emergency. It must be treated immediately because it can quickly become fatal.

The body normally has the capacity to control and regulate its temperature. Heatstroke occurs when this mechanism is overwhelmed. The body’s temperature rises rapidly, and the person can’t cool down.