24 June 2026

The bacterium Neisseria gonorrhoeae has evolved resistance to most antibiotics used to treat it, but a machine-learning screen reveals potential therapies.

A molecule flagged by an artificial-intelligence tool kills Neisseria gonorrhoeae bacteria (artificially coloured) that are resistant to several antibiotics. Credit: CNRI/SPL

Scientists have used a machine-learning strategy to discover antibiotics with fresh mechanisms, including two that do not structurally resemble antimicrobial drugs already in use1.

Access options