With temperatures potentially reaching up to 40C this week, here are five medications that can make it harder to cope in the heat...Antidepressants - Specific antidepressants, including selective serotonin reuptake inhibitors (SSRIs) and tricyclics (TCAs), may exacerbate summer heat due to their impact on the body's sweating ability. Antipsychotics - Antipsychotics are prescribed to treat psychosis, and function by blocking the neurotransmitter dopamine. This subsequently affects levels of the neurotransmitter serotonin, which can lead to the hypothalamus’ impaired ability to sense and respond to changes in body temperature. Heart medications - Common medications for heart conditions and high blood pressure, including beta-blockers, diuretics, ramipril, and losartan, can hinder the body's ability to regulate temperature or increase the risk of dehydration during hot weather. Stimulants - Stimulants, such as amphetamines used for ADHD, affect brain chemicals like dopamine and noradrenaline, which can increase body temperature, boost metabolism, and alter sweating, making it harder for the body to cool down. Insulin - Warm temperatures cause blood vessels to dilate, leading to faster insulin absorption and a faster drop in blood sugar, potentially causing hypoglycemia, while heat can also grade insulin, reducing its effectiveness. In fullFive common medications that make it harder to cope in the heat