June 19, 2026
5 min read
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NEW ORLEANS — Once-daily orforglipron induced greater reductions in HbA1c than dapagliflozin and oral semaglutide for adults with type 2 diabetes, according to findings from the ACHIEVE-2 and ACHIEVE-3 trials. As Healio previously reported from the ACHIEVE-1 trial, orforglipron (Foundayo, Eli Lilly), a small molecule oral GLP-1, conferred greater decreases in HbA1c and body weight at 40 weeks
June 19, 2026
5 min read
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NEW ORLEANS —Adults with type 2 diabetes receiving once-daily orforglipron alongside insulin glargine had greater improvements in…

Lilly's oral GLP-1 Foundayo (orforglipron) delivered superior A1C control and weight loss in three pivotal type 2 diabetes trials

ACHIEVE-5 tested the oral GLP-1 drug in combination with a basal insulin regimen

With an obesity green light already in hand, Eli Lilly is pushing for its newly launched Foundayo (orforglipron) to break into…

ACHIEVE-5 trial showed improved glycemic control with less insulin and no added hypoglycemia

Daily orforglipron tablets led to greater weight loss than semaglutide tablets, offering potential oral alternative to Wegovy and…