A recent study suggests antidepressants and antipsychotics may effectively manage pain, offering a safer alternative to opioids without their addictive risks.
UCSF researchers mapped antidepressants and antipsychotics as opioid alternatives for specific pain types, reducing crisis misuse. Genetic variation in medication response drives demand for pharmacogenomic profiling and AI-powered clinical decision support integration.
The study was conducted by University of California, San Francisco
Jun 14, 2026
06:10 pm
What's the storyA recent study has suggested that a variety of psychiatric medications could be used as alternatives to powerful opioids for pain relief in emergency departments.
The research, conducted by Akash Shanmugam, a medical student at the University of California, San Francisco (UCSF), looked at non-opioid medications available at San Francisco General Hospital and existing medical literature.
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