“I’ve been waiting for this moment,” says Anna Faris.

The celebrated actress and comedian is on top of the box office once more, as “Scary Movie,” the sixth installment in the popular horror-spoof series, opened to a franchise-best $55 million last weekend. It all came to fruition thanks to Marlon Wayans, whose family was callously kicked off the films by Harvey and Bob Weinstein after the second installment.

One of the first things Wayans did when he got back the keys to “Scary Movie” was recruit stars Anna Faris and Regina Hall to return as Cindy Campbell and Brenda Meeks, its two embattled protagonists who’ve once again found themselves in the crosshairs of Ghostface, a psycho killer who really has it out for them.

“Scary Movie” was a blessing for Faris, who’d experienced a number of personal and professional hardships, from a public divorce to a career slowdown after exiting her CBS sitcom “Mom” in 2020 during COVID. But now, she’s never been in more demand. After “Scary Movie,” she’ll star in three more films out this year, including the screwball comedy “Spa Weekend” and the dark drama “Primetime,” opposite Robert Pattinson.

In a candid conversation via Zoom from her cabin in the woods of Washington, Faris opened up about her highs and lows, and how the success of “Scary Movie” seems like “one big victory lap.”