Israel said Monday it had struck targets across Iran, defying US President Donald Trump's call to refrain from retaliating against Tehran's barrage of missiles.The attacks further rattled a fragile April 8 truce as the war entered its 100th day, with the United States struggling to conclude a deal with Tehran to end the conflict.Explosions were heard in three cities including Tehran, according to Iranian state TV, as the Israeli military said it struck targets in western and central Iran.The Israeli barrage was tit-for-tat action against Iran's assault on Sunday of 11 missiles, all of which were intercepted, with no casualties.Trump had sought to rein in Israeli Prime Minister Benjamin Netanyahu, as Israel accused Tehran of making a "grave mistake". "I am going to call Bibi right now and tell him not to retaliate," Trump was quoted as saying by Axios journalist Barak Ravid in a phone interview, using Netanyahu's nickname."Israel had its strike and Iran had its strike. We don't need another one," Trump reportedly said. Ravid later posted that a US official said Trump spoke with Netanyahu, although the White House and Trump have yet to comment. British Foreign Secretary Yvette Cooper joined the pleas for restraint."The resumption of conflict between Iran and Israel is in no one's interest," she wrote on X, calling for diplomacy.- Warning -Tehran has insisted any deal to permanently end the war must also halt the parallel conflict in Lebanon, where Israel is pursuing a campaign against the Iran-backed movement Hezbollah, and had warned that any new attacks on Beirut would trigger a "full-scale resumption" of hostilities.Iranian foreign ministry spokesman Ali Safari told Al-Mayadeen television that Tehran's strikes came after weeks of restraint against Israeli aggression, local media reported.Iran's powerful Revolutionary Guards called the attack a "warning" after Israel struck Beirut's southern suburbs earlier in the day, threatening wider strikes in the event of repeated aggression.A separate Iranian attack targeting the headquarters of "terrorist groups" in Iraqi Kurdistan on Monday added yet more strain to hopes for a lasting peace.The Iranian government accuses the armed Kurdish parties of serving Western or Israeli interests.The Israeli army also said Monday it was working to intercept a missile launched from Yemen, where rebels have previously launched attacks on Israel.