On Monday, Serena Williams announced she's coming out of retirement for a wild card doubles match in London next week.

Gilbert Flores/Variety via Getty Images

The GOAT is bounding out of retirement.Tennis great Serena Williams is back in the game, after openly endorsing GLP-1s for weight loss, and emphasizing how great her knees feel at her new, lower weight."I'm moving better on Ro," she said in a Super Bowl ad for Ro, a telehealth company that prescribes Ozempic, Wegovy, and Zepbound. (Williams' husband, Reddit cofounder Alexis Ohanian, sits on the board and is a major investor.)In the commercial, Williams said she can move more easily and enjoy steadier blood sugar levels throughout the day while she trains. In general, she feels "healthier" on her injectable medication, which she's said helped her lose 34 pounds after the birth of her second child in 2023."After having two kids, I wasn't able to be at a weight that was healthy for me," Williams told the "Today" show when she first announced her paid partnership with Ro in 2025.Her comeback is huge for tennis, of course — but also for the burgeoning peptide movement.

Serena Williams said she lost 34 pounds on GLP-1 drugs from Ro. Her husband was an early investor in the telehealth company.