Pediatrix Medical Group Announces Publication of New Research Addressing Urgent Questions in Neonatology

Research Was Conducted Utilizing the Proprietary Pediatrix Clinical Data Warehouse

Pediatrix® Medical Group, Inc. (NYSE: MD), a leading provider of physician services, today announced the publication of new research on probiotic use and necrotizing enterocolitis (NEC) in preterm infants, addressing pressing questions about one of the most controversial issues in the field of neonatology. The research was conducted by clinicians affiliated with the Pediatrix Center for Research, Education, Quality and Safety in collaboration with the NEC Society, utilizing data from the Pediatrix Clinical Data Warehouse (CDW), one of the largest databases of neonatal outcomes in the world. Data from the Pediatrix CDW has been utilized in more than 250 peer-reviewed publications.

Published in the Journal of Perinatology, a large multicenter study of more than 10,000 extremely preterm infants found that rates of NEC, a serious and potentially life-threatening intestinal disease, rose in hospitals that sharply reduced probiotic use after the U.S. Food and Drug Administration’s (FDA) 2023 warning actions and market withdrawal of probiotics commonly used in NICUs. Because of the low incidence of NEC, a large cohort is critical, particularly in a retrospective study of this kind, demonstrating the importance of the Pediatrix CDW, which may be the only database capable of answering research questions like this relatively quickly.