— ASCENT-04 analysis finds PFS2 advantage as an indicator of long-term clinical benefit

by Wayne Kuznar, Contributing Writer

June 2, 2026

• 3 min read

CHICAGO -- Sacituzumab govitecan (SG, Trodelvy) added to pembrolizumab (Keytruda) extended a surrogate measure of long-term clinical outcomes compared with chemotherapy plus pembrolizumab in patients with PD-L1-positive metastatic triple negative breast cancer (mTNBC), according to an analysis of the phase III ASCENT-04 trial.