The neurosurgeon has no visual field. There is only a catheter, fed into the skull through a hole, no bigger than the tip of a crayon, and a set of coordinates that correspond to a target deep within the brain.A trajectory has been plotted from MRI scans taken with a stereotactic frame bolted to the patient’s head, a reference system that turns the brain’s interior into a 3D grid.The catheter advances along a pre-plotted line toward its destination: the striatum — specifically, the subcortical structures key to movement and thought, and among the first destroyed by Huntington’s disease.

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